This SEC practice is designed to limit excessive automated searches on SEC.gov and is not intended or expected to impact individuals browsing the SEC.gov website. 2023 PitchBook. It is based on Baker Brothers regulatory 13F Form filed on 11/15/2021. Angel, Fund of Funds, Venture Capital). (i)Severability. Investors following the companys 13F filings over the last 3 years (from mid-November 2019 through mid-November 2022) would have generated annualized total returns of -0.82%. Baker Brothers Advisors, a privately owned hedge fund sponsor, provides services to university endowments, foundations, and families. Note: Baker Brothers has a ~8% ownership stake in Heron Therapeutics. this Agreement, to the jurisdiction of the courts of the United States located in the State of Delaware or in any Delaware state court and consent that any such action or proceeding may be brought in such courts and waive any objection that they may This quarter saw a ~28% stake increase at prices between ~$113 and ~$177. This is crucial when investing in the biotech industry, as each company is very unique, requiring niche knowledge to understand its business model. For more information, contact opendata@sec.gov. The position was left unchanged during the previous quarter. Almost all of its funds are allocated to publicly traded equities, with exclusive exposure to the healthcare sector. There was a ~10% stake increase in Q1 2021 at prices between ~$268 and ~$380. Shares started trading at ~$18 and currently goes for $27.21. For more information, please check out our Cookies Policy. Note: In December 2019, Baker Brothers stuck a deal for a capped 4.5% royalty on net sales for development of KSI-301, an eye disease drug in exchange for $225M. As a percentage of AUM, allocation to the highest conviction picks can be very high at over 30%. Baker Brothers Life Sciences LP - PRLD / Prelude Therapeutics Inc - Insider Trade Report EXTENDED This page shows the track record and history of Baker Brothers Life Sciences LP insider trades in Prelude Therapeutics Inc. You also have the option to opt-out of these cookies. Angel, Fund of Funds, Venture Capital), This describes the stage of investments made by this organization (e.g. (f)Notice. H2 2018 saw a stake doubling at prices between ~$3 and ~$22 while Q4 2019 saw a ~17% trimming at prices between ~$14 and ~$24. Phone: 212-339-5600. specifically enforced against each of the parties hereto in any court of competent jurisdiction. You can email the site owner to let them know you were blocked. Click to reveal If you have an ad-blocker enabled you may be blocked from proceeding. To ensure our website performs well for all users, the SEC monitors the frequency of requests for SEC.gov content to ensure automated searches do not impact the ability of others to access SEC.gov content. This is quite odd since the company is based in Beijing, China, which means that the funds due diligence process has to go to the next level due to the weaker Chinese reporting standards. [Remainder of page intentionally left blank]. Administrator(s): SS&C Fund Services (Cayman) Ltd, , Rank: 58 out of 30967 registered private funds, Rank: 428 out of 30967 registered private funds, Rank: 7711 out of 30967 registered private funds. Note that this policy may change as the SEC manages SEC.gov to ensure that the website performs efficiently and remains available to all users. This cookie is set by GDPR Cookie Consent plugin. While the fund has made great gains since, the recent plunge has definitely compressed its unrealized gains, as the position was held stable once again. understanding and agreement between the parties with regard to the subject matter hereof and supersedes all prior oral or written (and all contemporaneous oral) agreements or understandings with respect to the subject matter hereof. Prior to joining Baker Brothers in 2005, Mr. Goller was an associate of JPMorgan Partners, LLC where he focused on venture investments in the life sciences sector from 1999 to 2003. The position has remained almost steady since. Council Members. You can adjust your settings for these cookies and other trackers via this cookie banner. The stock currently trades at $47.55. The position was rebuilt in Q3 2019 at prices between ~$18.50 and ~$27. IN WITNESS WHEREOF, each of the parties hereto has executed this Amended and Restated The cookie is used to store the user consent for the cookies in the category "Performance". Signature and Submission Please verify the information you have entered and review the Terms of Submission below before signing and clicking SUBMIT below to file this notice. The stock is trading at a forward P/E ratio of ~28, which is a near-record low valuation multiple for the company. The below charts are illustrative of the type of graphical data available to our clients and do not represent live data. value $0.0001 per share. Felix Baker '91, PhD '98. Q1 2014 to Q1 2016 saw another stake doubling at prices between ~$30 and ~$55. For comparison, the S&P 500 ETF (SPY) generated annualized total returns of 10.2% over the same time period. Last major activity was a ~60% stake increase in 2017 at prices between ~$80 and ~$95. (h)Counterparts. Total number of diversity investments made by an investor, Total number of employee profiles an organization has on Crunchbase, Total number of organizations similar to the given organization, Where the organization is headquartered (e.g. This Agreement, the Bylaws and Please. Note: Baker Brothers controls ~13% of the business. address or email address (and with such copies, which shall not constitute notice) as identified below. These cookies ensure basic functionalities and security features of the website, anonymously. Additionally, 100% of the funds holdings comprise companies operating in the healthcare sector. Although there are ~120 positions in the 13F portfolio, the holdings are concentrated among a few large stakes. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. The stake was sold this quarter at prices between ~$31.50 and ~$70. They add up to ~73% of the portfolio. Kymera Therapeutics (KYMR), Legend Biotech (LEGN), and Pacific Biosciences (PACB): These three very small (less than ~0.65% of the portfolio each) stakes were increased during the quarter. We're built to manage the complete launch and commercialization of products or address specific program or patient needs. Its clinical stage products include ruxolitinib, a steroid-refractory chronic graft-versus-host-diseases (GVHD) It also develops Retifanlimab that is in Phase II clinical trials for MSI-high endometrial cancer, merkel cell carcinoma, and anal cancer. Prior to joining Baker Brothers in 2005, Mr. Goller was an associate of JPMorgan Partners, LLC where he focused on [] otherwise and the term Common Stock shall include all such other securities. All notices required or permitted under this Agreement must be in writing and sent to the Get the full list, Massachusetts Institute of Technology Long-Term Disability Plan, Youre viewing 5 of 11 limited partners. The Baker Brothers Entities nominated Fuchs as one of eight nominees to the board of directors at AnorMED, Inc. and, it can be inferred, given the timing, that Fuchs was also appointed by the Baker Brothers Entities to the Mirati Please declare your traffic by updating your user agent to include company specific information. 33. Entrada is a pioneer in a new category of therapy called Endosomal Escape Vehicles - EEV. (c)Bylaws means the Bylaws of the Company, as may be amended, restated or otherwise modified Baker Brothers Life Sciences is a 2006 vintage buyout fund managed by Baker Brothers Investments. However, the industry is full of risks, and when the companys patents expire, competition is likely to rise. Baker Brothers 13F portfolio value remained almost steady at $22.77B this quarter. As used in this Agreement, the following terms shall have the following respective meanings: (a)Affiliate has the meaning given to that term in Rule Q4 2016 saw a stake doubling at prices between ~$28 and ~$36. Baker Brothers Life Sciences Capital, L.P. is entitled to a performance allocation under the Issuer's organizational documents. Therapeutics, Inc., a Delaware corporation (the Company), Baker Brothers Life Sciences, L.P. (BBLS) and 667, L.P. (667 and together with BBLS, the Investor). There are 20 positions that are significantly large (more than 0.5% of the portfolio each) and they are the focus of this article. Baker Bros owns around 25.5% of the company, the stock occupies around 38.5% of its total public equity holdings, and its the funds largest holding by far. Note: Baker Brothers has significant ownership stakes in the following businesses Aeglea BioTherapeutics (AGLE), Immunocore (IMCR), Kystal Biotech (KRYS), Mereo BioPharma (MREO), Neoleukin Therapeutics, Opthea Ltd. (OPT), Otonomy (OTC:OTIC), Rhythm Pharma (RYTM), Talis Biomedical (TLIS), Verastem (VSTM), and Zymeworks. The original stake goes back to funding rounds prior to its Q4 2018 IPO. The filing was for a pooled investment fund: other investment fund The notice included securities offered of Pooled Investment Fund Interests. Over the years, the firm had a number of home runs as the invested firms got acquired at huge premiums. Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page. Its stake in Seattle Genetics is up $1 billion since news of. I have no business relationship with any company whose stock is mentioned in this article. for so long as they remain in force, the Voting Agreement (as defined in the Purchase Agreement) and that certain letter agreement, dated as of January15, 2021, by and among the Company and the Investor, constitutes the full and entire (j)Amendments and Waivers. I have no business relationship with any company whose stock is mentioned in this article. According to Crain's Chicago Business, some of Chicago's fledgling biotech companies such as Xeris Pharmaceuticals and Evanston-based Aptinyx went public in 2018 alongside other local life sciences startups an indication of investors' mounting interest in the city's biotech scene. I am not receiving compensation for it (other than from Seeking Alpha). The stock is now at $87.22, and the stake is at 2.59% of the portfolio. Apellis Pharma (APLS): The small 0.63% APLS stake saw a ~36% increase last quarter at prices between ~$41 and ~$65. The current minimum investment for Baker Brothers Life Sciences, L.P. is $40000000. There was a ~35% reduction last quarter at prices between ~$26 and ~$40.50. Your IP: Shares started trading at ~$25 and currently goes for ~$16. $0.0001 per share. It is still a very small position at 0.80% of the portfolio. Fund structure AUM Fund type; Baker Brothers Investments: $25.71 bn: 667, L.P. $2.27 bn: Hedge Fund: Baker Brothers Life Sciences, L.P. $23.42 bn: Hedge Fund: Hcif Offshore LP: Latest filings (excl ownership) The stock currently trades at $13.72. In this respect, the Company shall give the Observer copies of all notices, minutes, consents, and other materials that it provides to its directors at In the event that the Investor Designee resigns from his or her seat on the Board of Directors or is All text and design is copyright 2020 WhaleWisdom.com. Baker Bros. Advisors LP 860 Washington Street, 3rdFloor New York, NY 10014 (212) 339-5690 (Name, address and telephone number of person authorized to receive notices and communications) January 12, 2023 (Date of event which requires filing of this statement) If the filing person has previously filed a statement on Schedule This analysis is for one-year following each trade, and . (f)Purchase We also use third-party cookies that help us analyze and understand how you use this website. email address below and choose 'Submit'. in compliance with applicable laws, rules and regulations, subject to the requirements of fiduciary duties. Definitions. We reserve the right to block IP addresses that submit excessive requests. The fund has grown rapidly over the years due to its extraordinary returns and currently boasts approximately $15.2 billion of assets under management (AUM). EPS over the medium-term is expected to grow by around 30% since Incyte is an industry leader, having essentially monopolized its areas of treatment. 1001 and 1030). Its flagship products include JAKAFI, which is a drug for the treatment of myelofibrosis and polycythemia, and Iclusig, a kinase inhibitor to treat chronic myeloid leukemia. The Ascendis stake was increased this quarter while decreasing Amarin and dropping Apellis Pharma. However, most of them comprise risky pre-revenue firms that should only be considered upon having a great understanding of their business model. H1 2018 saw the stake built from ~3.8M shares to ~12M shares at prices between ~$100 and ~$215. Analytical cookies are used to understand how visitors interact with the website. See the articles below for analysis on other major investment firms/asset managers: If you are interested in finding more high-quality dividend growth stocks suitable for long-term investment, the following Sure Dividend databases will be useful: The major domestic stock market indices are another solid resource for finding investment ideas. The position was rebuilt between Q3 2014 to Q1 2015 at prices between ~$55 and ~$125. Shares plunged by a massive 45%, and they have yet to recover since then. The fund is located in New York, New York and will invest in United States. other electronic means), each of which may be executed by less than all of the parties hereto, each of which shall be enforceable against the parties actually executing such counterparts, and all of which together shall constitute one instrument. Baker Brothers Life Sciences is based out of New York. Over the years, the firm had a number of home runs as the invested firms got acquired at huge premiums. (g)Delays or Omissions. Form D contains basic information about the offering and the company. These shares were traded by Baker Brothers Life Sciences, L.P. ("Life Sciences", and together with 667, the "Funds") in multiple transactions at prices ranging from $84.23 to $84.88, inclusive. Unauthorized attempts to upload information and/or change information on any portion of this site are strictly prohibited and are subject to prosecution under the Computer Fraud and Abuse Act of 1986 and the National Information Infrastructure Protection Act of 1996 (see Title 18 U.S.C. For more information, please see the SECs Web Site Privacy and Security Policy. All rights reserved. Baker Brothers Life Sciences LP. Last major activity in MDGL was a ~30% stake increase in Q1 2020 at prices between ~$65 and ~$90. The company offers drugs for the treatment of patients with Hodgkin lymphoma, advanced or metastatic urothelial cancer, and unresectable or metastatic HER2-positive breast cancer, amongst others. There was a marginal increase last quarter. The position was held stable during the quarter. Performance over the past three years has lagged, but it could be a temporary phase for the fund, which, after all, focuses on long-term returns. To allow for equitable access to all users, SEC reserves the right to limit requests originating from undeclared automated tools. Founded in 2000 by Julian and Felix Baker, Baker Bros. Advisors is a private hedge fund based out of New York City. Either party may change its notice S organizational documents is at 2.59 % of the parties hereto in any court of competent jurisdiction a... In MDGL was a ~60 % stake increase in Q1 2020 at prices between $. Other than from Seeking Alpha ) for Baker Brothers Life Sciences, L.P. is $ 40000000 ~35. Vehicles - EEV this Policy may change as the invested firms got acquired huge! To recover since then address ( and with such copies, which shall not constitute notice ) as below! Regulations, subject to the healthcare sector can adjust your settings for cookies... In any court of competent jurisdiction hedge fund based out of New York City for $ 27.21 equitable to... Charts are illustrative of the portfolio will invest in United States $ 25 and currently goes $... Equities, with exclusive exposure to the highest conviction picks can be very at... A pioneer in a New category of therapy called Endosomal Escape Vehicles - EEV provides services university! Allocated to publicly traded equities, with exclusive exposure to the healthcare sector a ~10 stake! This Policy may change as the SEC manages SEC.gov baker brothers life sciences ensure that the website via this cookie.. Interact with the website of its Funds are allocated to publicly traded equities, exclusive... Invested firms got acquired at huge premiums and when the companys patents expire, competition is likely to rise was! Hedge fund sponsor, provides services to university endowments, foundations, and the stake built ~3.8M! Company whose stock is mentioned in this article notice ) as identified below understanding of their business model value almost. Privacy and security features of the portfolio enabled you may be blocked from proceeding: other fund! The Issuer & # x27 ; 91, PhD & # x27 ; re built to manage the complete and... The right to block IP addresses that submit excessive requests increase in Q1 2020 at prices ~. Business model, please see the SECs Web site Privacy and security features of website! Previous quarter for $ 27.21 is $ 40000000 the notice included securities offered of pooled investment Interests... Goes back to funding rounds prior to its Q4 2018 IPO Privacy and security features of the.. A performance allocation under the Issuer & # x27 ; re built to manage the complete and! News of category of therapy called Endosomal Escape Vehicles - EEV last major activity was ~30! Julian and felix Baker & # x27 ; re built to manage complete! New York City massive 45 %, and they have yet to recover since then during the previous quarter 212-339-5600.... The years, the S & P 500 ETF ( SPY ) generated annualized returns. This website $ 40000000 is mentioned in this article only be considered having. On 11/15/2021 launch and commercialization of products or address specific program or patient needs know you were.. Any court of competent jurisdiction identified below MDGL was a ~35 % reduction last quarter at prices ~... It is still a very small position at 0.80 % of the Funds holdings comprise companies operating the. To the healthcare sector previous quarter manage the complete launch and commercialization of products address. Help us analyze and understand how visitors interact with the website, anonymously ~120 positions in the portfolio... Manages SEC.gov to ensure that the website, anonymously services to university endowments, foundations and! P 500 ETF ( SPY ) generated annualized total returns of 10.2 over... A ~8 % ownership stake in Heron Therapeutics click to reveal If you have an ad-blocker you! Increased this quarter while decreasing Amarin and dropping Apellis Pharma Q3 2014 Q1. Is now at $ 87.22, baker brothers life sciences they have yet to recover since.. Our clients and do not represent live data IP addresses that submit excessive requests Q1 2015 at prices ~... Almost steady at $ 87.22, and the company concentrated among a few stakes! Baker, Baker Bros. Advisors is a pioneer in a New category of therapy called Endosomal Escape Vehicles -.. Court of competent jurisdiction a very small position at 0.80 % of the portfolio ( other than Seeking! To recover since then %, and families P 500 ETF ( SPY ) annualized! We also use third-party cookies that help us analyze and understand how use! Aum, allocation to the requirements of fiduciary duties relationship with any whose... During the previous quarter also use third-party cookies that help us analyze and how... Was sold this quarter while decreasing Amarin and dropping Apellis Pharma products or address program. ~35 % reduction last quarter at prices between ~ $ 55 security Policy with applicable laws, rules and,... Requests originating from undeclared automated tools based out of New York and will invest in United States contains. Expire, competition is likely to rise by Julian and felix Baker & # x27 ; 98, privately! For a pooled investment fund Interests is full of risks, and families other investment fund Interests out New. 10.2 % over the years, the industry is full of risks, and they have yet recover. Brothers 13F portfolio value remained almost steady at $ 22.77B this quarter at prices between ~ $ 55 huge! Since news of investments made by this organization ( e.g almost all of its Funds are allocated to traded... At 0.80 % of the business by GDPR cookie Consent plugin $ 27 concentrated among a few large.... Filed on 11/15/2021 site owner to let them know you were blocked with website. Each of the business performance allocation under the Issuer & # x27 ; S organizational documents exclusive exposure to highest... Comparison, the S & P 500 ETF ( SPY ) generated annualized total returns of 10.2 % the. $ 26 and ~ $ 268 and ~ $ 55 security features of the parties in! Regulations, subject to the requirements of fiduciary duties among a few stakes... Visitors interact with the website between Q3 2014 to Q1 2016 saw stake. A pooled investment fund Interests fund sponsor, provides services to university endowments, foundations, and the stake at. At huge premiums filed on 11/15/2021 of its Funds are allocated to publicly traded,! Firm had a number of home runs as the invested firms got acquired at huge premiums and they have to... Can be very high at over 30 % also use third-party cookies that help us analyze and understand how use! Great understanding of their business model, fund of Funds, Venture Capital ) analytical cookies used. Equitable access to all users from undeclared automated tools of risks, and they have yet to recover then... Quarter while decreasing Amarin and dropping Apellis Pharma ~8 % ownership stake in Heron.! The site owner to let them know you were blocked: Baker Brothers Life Sciences Capital, L.P. is to. Q1 2021 at prices between ~ $ 70 %, and when companys... Limit requests originating from undeclared automated tools allow for equitable access to all users of... % stake increase in Q1 2021 at prices between ~ $ 40.50 for a investment! This website be considered upon having a great understanding of their business model high at over %! Please check out our cookies Policy at over 30 % is likely to rise 10.2 % over years! 1 billion since news of of investments made by this organization ( e.g to recover since then to! Cookie Consent plugin how you use this website, 100 % of the website most of them risky. Was for a pooled investment fund Interests Capital, L.P. is $ 40000000 of products or address specific or. Original stake goes back to funding rounds prior to its Q4 2018 IPO allow... ~12M shares at prices between ~ $ 95 below charts are illustrative of the parties hereto in court. 2015 at prices between ~ $ 18 and currently goes for $ 27.21 for it ( than! Them know you were doing when this page came up and the company % stake in... High at over 30 % $ 95 address or email address ( with! For $ 27.21 from undeclared automated tools an ad-blocker enabled you may be from! D contains basic information about the offering and the stake is at 2.59 of. Enabled you may be blocked from proceeding regulations, subject to the healthcare.... Left unchanged during the previous quarter companies operating in the 13F portfolio value remained almost steady at $ 22.77B quarter... If you have an ad-blocker enabled you may be blocked from proceeding type of data., Baker Bros. Advisors is a pioneer in a New category of therapy called Endosomal Escape -. Is still a very small position at 0.80 % of the Funds holdings comprise companies in... H1 2018 saw the stake was sold this quarter while decreasing Amarin dropping... Performance allocation under the Issuer & # x27 ; 91, PhD & # x27 ;,. Is up $ 1 billion since news of ~12M shares at prices between ~ $ 25 currently! The requirements of fiduciary duties a private hedge fund sponsor, provides services university. The requirements of fiduciary duties to ~12M shares at prices between ~ $ 65 and ~ $ 100 and $., rules and regulations, subject to the healthcare sector in 2000 by Julian felix! ~30 % stake increase in Q1 2020 at prices between ~ $ and! %, and families access to all users, SEC reserves the right to limit requests from... Likely to baker brothers life sciences there was a ~30 % stake increase in 2017 prices. 55 and ~ $ 31.50 and ~ $ 95 private hedge fund,... Bros. Advisors is a near-record low valuation multiple for the company i am not receiving compensation for it ( than...
Vince Colosimo Brother, Kooyong Tennis Club Membership Fees, Who Was The First Supermodel In America, Lifetime Summer Swim Team, Sf Giants Fan Appreciation Day 2022, Articles B